New Orleans to Memphis Road Trip Guide

Introduction

Follow the rhythm of American music up I-55 from jazz-soaked New Orleans to blues-drenched Memphis on this soulful 395-mile journey through the heart of the Deep South. This iconic route traces the Mississippi Blues Trail through Louisiana and Mississippi, connecting two of America's most legendary music cities with stops in Jackson's cultural district and Clarksdale's juke joints along the way. The best time to travel is spring (March-May) or fall (September-November) when temperatures stay comfortable and festival season brings the music scene alive. Perfect for couples and small groups seeking an easy point-to-point getaway, this drive delivers Southern hospitality, mouthwatering cuisine, and the soundtrack of rock 'n' roll, blues, and jazz that changed the world.

Ready to hit the road? Start your journey with New Orleans RV rentals or explore options from Memphis RV rentals if you're heading south.

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Details

60'
Max RV length
60'
Max trailer Length
Road trip length: 2-3 days
Recommend rig: any
audience: couple

RV Rentals in New Orleans, LA

Point of Interest

Mississippi Agriculture Museum

Any great road trip can't be all about one topic. Here is a great non-music related stop on our tour which can be visited during the daylight hours. The Mississippi Agriculture and Forestry Museum is a living history museum modeled after a 1920's town and designed to highlight the agrarian history of the region. The museum, located outside Jackson, MS, encompasses 39 acres of land and has over 29 exhibits in the form of a small rural Mississippi town. It includes a heritage center, agricultural gardens, display gardens, a children's barn, agricultural aviation museum, a nature trail, a farmstead, and general store.

LeFleur's Bluff State Park provides a good camping spot for RVs or tents near town. They have 27 developed sites in a beautiful park setting just outside of town.


Fondren District

The Fondren District is the hip hotspot of the arts and entertainment in Jackson, MS. This thriving section of town makes for a great night or evening out on the town with numerous live music venues, restaurants, shops, art galleries, and other venues. Each week brings new and exciting experiences in the are including indoor and outdoor live music performances, food tasting events, and art shows.

The main entertainment areas center around the historic downtown district around Fondren Pl, Duling Ave, Old Canton Road, State Street, and Lakeland drive. Additional sections are a couple of blocks north between Meadowbrook Road and Northside Drives along State Street and Northview Drive. The third block is centered around exit 100 off I-55. All these areas are walkable and make for a great night out on the town.


Ground Zero Blues Club

The Ground Zero Blues Club is located about 45 minutes west of I-55 in Clarksdale, MS. The club is co-owned by Morgan Freeman and gets its name from the widely accepted notion that Clarksville, MS is the historical “ground zero” of blues music in the US. If you want to experience the blues where it all began in an authentic delta blues environment, you can't do much better then here. The club itself is located in an old building with tons of character. It is also home to some great food and you can even stay the night in one of the many hotel rooms located upstairs. This club has quite a following so expect top talent to be in the lineup on a nightly basis.

Isle of Capri Casino RV Park offers very affordable full hookup spaces in Lulu about a half-hour north of Ground Zero.


French Quarter & Bayou Segnette State Park

Start your journey by soaking in New Orleans's legendary French Quarter, where jazz spills from doorways and the smell of beignets fills the air. Bourbon Street, Jackson Square, and Café du Monde offer quintessential Big Easy experiences, while Frenchmen Street delivers authentic local music without the tourist crowds.

Bayou Segnette Campground sits just minutes south of downtown, offering the perfect blend of French Quarter access and peaceful swampland camping. This state-run park features spacious sites with electric and water hookups, wireless internet, a swimming pool, and hiking trails through genuine Louisiana bayou. Wake up to chirping birds, grab coffee by your RV, then head downtown for a full day of exploring.

Alternative New Orleans camping includes Fontainebleau State Park Campground, a 40-minute drive across Lake Pontchartrain with sandy beaches and cypress wetlands, or Pontchartrain Landing Campground, an upscale lakefront resort just minutes from the French Quarter with full hookups, pool, hot tub, and marina access.


Clarksdale & the Delta Blues Trail

This is where it all began. Clarksdale sits at the crossroads of the Delta blues, where legends like Muddy Waters, John Lee Hooker, and Ike Turner learned their craft. The Delta Blues Museum downtown preserves this heritage with Muddy Waters's actual cabin, rare instruments, and rotating exhibits that bring the music's history to life.

Ground Zero Blues Club, co-owned by actor and Mississippi native Morgan Freeman, serves up live music most nights along with cold beer and Delta soul food. The atmosphere feels authentic because it is—this isn't a tourist trap but a real juke joint where locals come to hear the blues.

While Clarksdale doesn't have dedicated RV parks, you can easily day-trip from Jackson (2 hours south) or continue to Memphis (70 miles north) for overnight camping. The detour adds about 30-45 minutes to your drive but delivers an experience you can't get anywhere else.


Graceland & Beale Street in Memphis

Your destination city delivers the full Elvis experience and is the birthplace of rock 'n' roll. Graceland, Elvis Presley's mansion-turned-museum, offers an intimate look at the King's life with his actual home, car collection, airplane, and final resting place. Book tickets ahead during peak season—this is one of America's most-visited homes.

Memphis Graceland RV Park and Campground puts you within walking distance of Graceland itself, offering full hookups with 30/50-amp electric, a swimming pool, a playground, and pet-friendly sites. The campground's proximity to the attraction means you can easily spend a full day exploring and then return to your RV for a relaxing evening.

Beale Street downtown pulses with live music every night—blues, rock, soul, and everything in between. Start at B.B. King's Blues Club, grab a bucket of dry rub ribs from any of the BBQ joints (locals argue fiercely about which is best), then bar-hop your way down the street as the music spills out of every doorway.

For alternative Memphis camping, Memphis KOA in nearby Marion, Arkansas (18 minutes from downtown) offers resort-style amenities including pool, camping kitchen, Wi-Fi, basketball court, and shuttle service to Memphis attractions. Memphis East Campground in Bartlett provides a quieter suburban setting with full hookups, a swimming pool, and a fishing pond.


Summary

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Frequently asked questions about New Orleans to Memphis Road Trip