RV rental Lake Santa Fe, FL: Motorhome rentals, camper van rentals and more

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Discover Lake Santa Fe RV rentals for memorable road trips

When you decide to rent an RV and take a road trip through Florida’s peninsula, make sure to stop off at scenic Lake Santa Fe. Located at the confluence of Route 301 and Route 24, Lake Santa F is a convenient stop for anyone driving from Gainesville or Palatka.

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How to rent a RV in Lake Santa Fe

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Getting Outdoors

Camping at Lake Santa Fe is most popular during the warmer months when visitors can take advantage of the lake’s boating opportunities. Encompassing nearly 6,000 acres of water, there are plenty of small coves and secluded bays to explore when you rent a camper near Lake Santa Fe. Whether you have your own boat in tow or need to rent one from a local outlet, visitors can use one of the many public boat ramps to access the lake’s waters including Melrose Marina or Little Santa Fe Boat Ramp. Whilst out on the waters keep an eye out for one of the many species of wading birds and waterfowl that inhabit the wetlands. Anything from Herons to Bitterns has been seen from Lake Santa Fe’s waters.

Camping at Lake Santa Fe

Unfortunately, RV camping on Lake Santa Fe isn’t possible, and those with an RV rental will need to search a little further afield to find a place to set up camp.

Exploring the Area

Lake Santa Fe is just a twenty-minute drive from Gainesville, a city that boasts a huge number of city attractions and family-friendly activities. One of Gainesville’s most popular attractions is The Florida Museum of Natural History. Located on the University of Florida’s campus, this free museum boasts over 40 million artifacts from the natural world. This includes the world’s largest collection of butterflies and moths as well as a huge collection of prehistoric fossils. Bring the kids and get them involved in one of the interactive workshops in the well-regarded Discovery Zone!

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Popular nearby hiking trails and campgrounds

  • Hiking TrailLocation
  • Mike Roess Gold Head Branch State Park Trail, FLKeystone Heights, FL
  • Morningside Nature Center Loop Trail, FLGainesville, FL
  • Susan Wright Trail, FLPaynes Prairie Preserve State Park, FL
  • The Florida Trail Segment 24: Holloway Road Trailhead to Gold Head Branch State Park Trailhead, FLMike Roess Gold Head Branch State Park, FL
  • Longleaf Flatwoods Reserve Trail, FLHawthorne, FL
  • Sweetwater Preserve Loop Trail, FLGainesville, FL
  • Gainesville-Hawthorne State Trail, FLGainesville, FL
  • La Chua Trail, FLGainesville, FL
  • Gainesville 6th Street Rail Trail, FLGainesville, FL
  • Loblolly Woods Trail, FLGainesville, FL

Recent RV rental reviews in Lake Santa Fe

Aubree G.

September, 2025

This rig was perfect for our family of 4 and can easily accommodate more, they have games under the kitchen chairs that we played with, chairs and rug for outside, coffee maker and much more! Greatly priced for everything you get! Jeremy was great at getting us set up with everything we needed. Super quick with responding to any questions or concerns!
Patrick D.

September, 2025

Zak was a great host. He set up the camper for us before we even knew he was there. Very clean camper, and the A/C kept us nice and cozy despite some very hot & humid temperatures.
Matthew G.

September, 2025

The host was very polite, accommodating, and responsive. Would book again.

Frequently asked questions about renting an RV near Lake Santa Fe

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