RV rental Lake Santa Fe, FL: Motorhome rentals, camper van rentals and more

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Discover Lake Santa Fe RV rentals for memorable road trips

When you decide to rent an RV and take a road trip through Florida’s peninsula, make sure to stop off at scenic Lake Santa Fe. Located at the confluence of Route 301 and Route 24, Lake Santa F is a convenient stop for anyone driving from Gainesville or Palatka.

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How to rent a RV in Lake Santa Fe

  • 1

    Search by location

    Tell us where in Lake Santa Fe you want to pick up or have your RV delivered

  • 2

    Filter search results

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  • 3

    Message the owner

    Learn more about your favorite RV and the best local destinations

  • 4

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    Send a request directly to the host and start preparing for your adventure

Getting Outdoors

Camping at Lake Santa Fe is most popular during the warmer months when visitors can take advantage of the lake’s boating opportunities. Encompassing nearly 6,000 acres of water, there are plenty of small coves and secluded bays to explore when you rent a camper near Lake Santa Fe. Whether you have your own boat in tow or need to rent one from a local outlet, visitors can use one of the many public boat ramps to access the lake’s waters including Melrose Marina or Little Santa Fe Boat Ramp. Whilst out on the waters keep an eye out for one of the many species of wading birds and waterfowl that inhabit the wetlands. Anything from Herons to Bitterns has been seen from Lake Santa Fe’s waters.

Camping at Lake Santa Fe

Unfortunately, RV camping on Lake Santa Fe isn’t possible, and those with an RV rental will need to search a little further afield to find a place to set up camp.

Exploring the Area

Lake Santa Fe is just a twenty-minute drive from Gainesville, a city that boasts a huge number of city attractions and family-friendly activities. One of Gainesville’s most popular attractions is The Florida Museum of Natural History. Located on the University of Florida’s campus, this free museum boasts over 40 million artifacts from the natural world. This includes the world’s largest collection of butterflies and moths as well as a huge collection of prehistoric fossils. Bring the kids and get them involved in one of the interactive workshops in the well-regarded Discovery Zone!

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Popular nearby hiking trails and campgrounds

  • Hiking TrailLocation
  • Mike Roess Gold Head Branch State Park Trail, FLKeystone Heights, FL
  • Morningside Nature Center Loop Trail, FLGainesville, FL
  • Susan Wright Trail, FLPaynes Prairie Preserve State Park, FL
  • The Florida Trail Segment 24: Holloway Road Trailhead to Gold Head Branch State Park Trailhead, FLMike Roess Gold Head Branch State Park, FL
  • Longleaf Flatwoods Reserve Trail, FLHawthorne, FL
  • Sweetwater Preserve Loop Trail, FLGainesville, FL
  • Gainesville-Hawthorne State Trail, FLGainesville, FL
  • La Chua Trail, FLGainesville, FL
  • Gainesville 6th Street Rail Trail, FLGainesville, FL
  • Loblolly Woods Trail, FLGainesville, FL

Recent RV rental reviews in Lake Santa Fe

Robert P.

July, 2025

we felt that the trailer was in superb condition with all of the items needed for camping. Manny was fantastic and showed these beginners how, what, and why of trailer life and all the tools built into the coach. Trailer was set up and ready to go when we arrived on site. Fantastic
Mike S.

July, 2025

This camper was perfect for just myself and wife for quick weekend away. Everything you need is stocked and available inside the camper. Host was very nice and helpful with any questions. Would definitely rent again.
Dana B.

July, 2025

The RV was wonderful! Very clean, perfectly stocked, modern, and plenty of room for our family. Hosts were great with communication and lovely to work with. Thank you for helping us make memories with our friends and family for another summer at Rainbow Springs!

Frequently asked questions about renting an RV near Lake Santa Fe

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